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US Study Shows Safe Daily CBD Dose is Up to 13 Times Higher Than What SAHPRA Allows

US Study Shows Safe Daily CBD Dose is Up to 13 Times Higher Than What SAHPRA Allows

There’s been a lot of controversy around acceptable daily doses of CBD, with SAHPRA setting a 20 mg limit. Now a US study headed for Congress says safe dosages could be 13 times higher, with up to 160 Mg of CBD/day being safe for most healthy adults.

TG Branfalt, The Ganjapreneur

21 September 2023 at 14:00:00

This report from Ganjapreneur, published first on 20 September 2023.


A coalition of CBD companies known as ONE HEMP, which aims to engage Congress and the Food and Drug Administration (FDA), have submitted a study to U.S. officials that shows upper intake limits of 70 milligrams of CBD per day is safe for healthy adults. 


The study also found upper intake limits of 160 milligrams per day are safe for healthy adults who are not trying to conceive, are pregnant, or lactating.


The study was submitted following a Request for Information from House and Senate committees and was specifically designed to address concerns previously raised by the FDA that CBD is potentially harmful to liver and reproductive health.


In a statement, Dr. Rayetta G. Henderson Ph.D., senior managing scientist at ToxStrategies LLC, which conducted the study, said the research found the suggested upper intake limits for CBD for healthy adults “closely correspond with the recommendations put forth by leading regulatory bodies,” including Health Canada, Australia’s Therapeutic Goods Administration, and the U.K.’s Food Standards Agency.


Dr. Marcel Bonn-Miller Ph.D., chief scientific officer at Charlotte’s Web and part of the research team, said the study “will help to inform legislators and regulators as they determine manufacturing and labeling requirements for supplement products containing CBD.”


“Implementing scientifically based safety limits is crucial to protecting consumers. This research is also aligned with ONE HEMP’s recommendations for accurate product labeling and, ultimately, holding CBD companies accountable for manufacturing and selling quality and safe products.” — Bonn-Miller in a press release.


Charlotte’s Web is a founding member of ONE HEMP, whose goal is to work toward more stringent regulatory standards, including independent third-party testing and accurate labeling, the company said in a press release.


Jared Stanley, co-founder and COO of Charlotte’s Web, said the CBD market needs “clarity and stability” and that “it is time for Congress to clarify the FDA’s mandate and definitively regulate CBD products as dietary supplements once and for all.”


The peer-reviewed study submitted by ONE HEMP was published online on 25 August 2023 in the Regulatory Toxicology and Pharmacology.

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